NRL is hiring for the position of Jr. Research Associate – Clinical Genomics at its Ahmedabad location. This is an on-site employee position for candidates with a Master of Science (MSc) qualification and skills in FFPE tissue processing, DNA/RNA extraction, nucleic acid quality control, and sample preparation for molecular testing.
Job Details
| Particulars | Details |
|---|---|
| Company | NRL |
| Job Title | Jr. Research Associate |
| Department/Specialization | Clinical Genomics |
| Job Category | Technical |
| Job Type | Employee |
| Location | Ahmedabad |
| Workplace Type | On-site |
| Qualification | Master of Science (MSc) |
Positions
NRL is recruiting for the Jr. Research Associate – Clinical Genomics position, focusing on FFPE tissue processing, nucleic acid extraction, sample quality assessment, and coordination with the next-generation sequencing (NGS) team.
Job Responsibilities
Selected candidates will be responsible for the following activities:
- Receive and process FFPE tissue blocks, slides, and tissue sections for molecular testing.
- Perform sample accessioning, maintain traceability, and update FFPE sample-processing logs.
- Carry out FFPE sectioning and prepare unstained sections and H&E-stained slides.
- Assess tumor presence, tumor cellularity, necrosis, and tissue adequacy in coordination with the pathologist or authorized personnel.
- Identify tumor-rich areas and perform macrodissection when required.
- Extract DNA and RNA from FFPE tissue using validated protocols.
- Evaluate DNA/RNA concentration, purity, quality, and quantity using appropriate QC methods.
- Document sample receipt, sectioning, extraction, QC results, and sample disposition.
- Identify and record insufficient tissue, low tumor cellularity, poor nucleic acid quality, and other sample-related QC failures.
- Coordinate with the NGS team regarding sample suitability, library preparation, and downstream testing.
- Handle, label, store, and track FFPE blocks, slides, extracted DNA/RNA, and residual samples.
- Follow laboratory SOPs, quality-control requirements, biosafety practices, and sample-traceability procedures.
- Maintain equipment, reagent, extraction, and sample-processing logs.
- Troubleshoot FFPE sectioning, tissue adequacy, DNA/RNA extraction, and QC issues, escalating problems when required.
Eligibility and Qualifications
- Educational Qualification: Master of Science (MSc).
- Candidates should have skills relevant to FFPE tissue processing, molecular sample preparation, and DNA/RNA extraction.
Required Skills
Candidates should have knowledge or skills in the following areas:
- FFPE tissue processing and sectioning.
- Tumor cellularity assessment and macrodissection.
- H&E slide preparation.
- DNA and RNA extraction from FFPE tissue.
- Nucleic acid quality control, including concentration, purity, quality, and quantity assessment.
- Sample accessioning, tracking, traceability, and documentation.
- Identification of tissue adequacy issues and QC failures.
- Troubleshooting pre-analytical issues.
- Laboratory SOP compliance, biosafety, and quality-control practices.
application Details
