Pfizer is hiring a Senior Associate, Central Monitor, Risk Based Monitoring in Chennai. The role focuses on Risk-Based Monitoring (RBM), clinical trial data quality, Key Risk Indicators (KRIs), signal and action management, and quality oversight.

The position works closely with global study teams and Clinical Data Scientists to support clinical-trial objectives while ensuring RBM activities follow protocols, ICH GCP, SOPs, corporate standards, and applicable regulatory requirements. Pfizer’s current career materials also describe Central Monitor roles as part of its Biometrics & Data Management organization

Pfizer Senior Associate Central Monitor Job 2026: Overview

About the Role

The Senior Associate, Central Monitor is responsible for supporting the completeness, quality, and integrity of subject data within clinical-trial databases under a Risk-Based Monitoring model.

The role combines clinical data review, RBM system configuration, KRI management, signal detection and action management, quality control, and stakeholder coordination. The position also involves troubleshooting RBM systems and working with global study teams to resolve identified issues.

Key Responsibilities

The Pfizer Senior Associate Central Monitor will be responsible for:

• Setting up and testing study-level Risk-Based Monitoring systems.
• Providing technical expertise for RBM system configuration.
• Reviewing study-level system outputs for signals and actions.
• Defining and configuring Key Risk Indicators (KRIs).
• Maintaining consistency between standard-level and study-level KRIs.
• Setting up dictionaries for Data Quality Assessment (DQA).
• Reviewing protocols to ensure RBM setup and reporting requirements can be met.
• Ensuring RBM systems align with clinical protocols and applicable standards.
• Supporting compliance with ICH GCP, SOPs, corporate standards, and regulatory requirements.
• Performing central monitoring activities and reviewing system outputs.
• Working with study teams to define resolution plans for findings.
• Following up on actions and issue resolution.
• Developing and maintaining RBM-related quality-control documentation.
• Working with Clinical Data Scientists to ensure signals and actions are appropriately addressed.
• Documenting lessons learned and sharing them across central monitoring teams.
• Providing technical oversight, guidance, and coordination for central monitoring activities.

These responsibilities are consistent with Pfizer’s published Central Monitor role descriptions, which include RBM system setup, KRI definition, data review, signal/action management, and clinical data collaboration.

The role specifically calls for knowledge or capability in areas including:

• Risk-Based Monitoring (RBM)
• Clinical trial data
• Key Risk Indicators (KRIs)
• Data Quality Assessment (DQA)
• Clinical study protocols
• Signal and action management
• Quality-control processes
• ICH GCP
• SOPs and regulatory requirements
• Clinical Data Management
• RBM system configuration and testing
• Stakeholder communication
• Issue investigation and resolution

Key Technical Areas

Risk-Based Monitoring

The position supports clinical-trial oversight using risk-based approaches rather than relying solely on traditional monitoring activities.

Key Risk Indicators

The Central Monitor helps define and configure KRIs used to identify potential risks within clinical-study data and processes.

Signal and Action Management

Study-level system outputs are reviewed to identify signals and coordinate appropriate actions and issue resolution.

Clinical Data Quality

The role focuses on maintaining the completeness, quality, and integrity of clinical-trial data.

Regulatory Compliance

RBM activities must align with applicable protocols, ICH GCP, SOPs, corporate standards, and regulatory requirements.

Benefits and Work Environment

The supplied job posting confirms a full-time hybrid work arrangement in Chennai.

Pfizer states on its careers pages that its benefits programs can include health and disability coverage, wellness programs, retirement-related benefits, insurance, paid time off, parental and caregiver leave, and country/site-specific programs. Exact benefits depend on the country and employment location

Who Can Apply?

This opportunity is particularly relevant to professionals working in areas such as:

• Clinical Data Management
• Risk-Based Monitoring
• Central Monitoring
• Clinical Research
• Clinical Data Science
• Clinical Trial Operations
• Clinical Database Management
• Data Quality
• Clinical Programming
• Regulatory Operation

How to Apply

Application Link