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Pfizer Scientist Small Molecule

Published on

PhD in Chemistry

Chennai

Verified Job

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Looking to advance your career in API process development and small molecule research? Pfizer is hiring a Scientist – Small Molecule Technology in Chennai, India. This role is ideal for PhD Chemistry professionals with strong expertise in organic synthesis, process optimization, and technology transfer.

This opportunity provides hands-on exposure to drug substance development, scale-up, and GMP manufacturing, making it highly valuable for candidates targeting R&D and MS&T roles in pharma.


🔬 Key Responsibilities

  • Perform literature search and identify synthetic routes for APIs, intermediates, and RSMs
  • Lead process development and optimization for yield improvement and cost reduction
  • Design and execute DoE (Design of Experiments) for robust process development
  • Conduct lab feasibility, optimization, pre-validation, and validation studies
  • Support technology transfer to manufacturing scale (plant level)
  • Troubleshoot scale-up challenges and process deviations
  • Develop and characterize process-related impurities
  • Ensure compliance with cGMP and safety procedures
  • Prepare scientific reports, protocols, and tech transfer documentation
  • Manage lab operations, inventory, and equipment qualification
  • Drive innovation projects in small molecule development

🎓 Qualifications Required

  • PhD in Chemistry (Mandatory)
  • Strong expertise in:
    • Organic synthesis & reaction mechanisms
    • API process development
    • Analytical characterization techniques
  • Knowledge of:
    • cGMP guidelines
    • Process validation and CPP
    • Technology transfer and scale-up
  • Skills:
    • Scientific writing & documentation
    • Cross-functional collaboration
    • Problem-solving in complex reactions

💼 Preferred Skills & Expertise

  • Experience in small molecule drug development
  • Understanding of impurity profiling and purification
  • Exposure to MS&T / Kilo Lab / Pilot Plant operations
  • Strong knowledge of process chemistry and industrial scale-up

💰 Salary Insight (India – Estimated)

  • ₹12 LPA – ₹22 LPA (based on experience and expertise)

🌟 Why Join Pfizer?

  • Global exposure in cutting-edge pharmaceutical R&D
  • Work on innovative small molecule drug pipelines
  • Strong learning environment with advanced technologies
  • Opportunity to contribute to life-saving medicines
  • Collaborative and research-driven culture

📍 Job Details

  • Role: Scientist – Small Molecule Technology
  • Location: Chennai, India
  • Department: Research & Development
  • Job Type: Full-Time (On-site)
  • Company: Pfizer

📩 How to Apply

Application Link

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