Meril has announced an opportunity for a Structural Biology Intern to work with its drug discovery programs in Delhi/Vapi, India. The internship is suitable for candidates from Structural Biology, Biophysics, Computational Biology and related disciplines who are interested in protein structure analysis, molecular modeling and structure-based drug discovery.
The selected candidate will contribute to therapeutic discovery programs involving protein-ligand interactions, molecular dynamics simulations, structure-based drug design and lead optimization. According to the job posting, the internship may also be converted into a full-time position based on performance.
This Meril Structural Biology Internship can be particularly relevant for BTech/MTech candidates seeking hands-on exposure to computational and structural biology within a multidisciplinary drug discovery environment.
Meril Structural Biology Intern – Job Overview
Company: Meril
Position: Structural Biology Intern
Job Type: Internship; potential full-time conversion based on performance
Locations: Delhi / Vapi, India
Workplace: On-site
Field: Structural Biology / Computational Biology / Drug Discovery
Qualification: BTech / MTech in Structural Biology, Biophysics, Computational Biology or related field
Posted Date: August 31, 2026
Key Responsibilities
As a Structural Biology Intern at Meril, the selected candidate is expected to contribute to structure-guided drug discovery and molecular modeling activities.
Key responsibilities include:
- Perform structure-based design of small molecules and protein therapeutics.
- Analyze protein-ligand interactions to support medicinal chemistry and lead optimization.
- Conduct molecular dynamics simulations to assess molecular complex stability.
- Perform free-energy calculations to investigate binding energetics.
- Apply structural biology insights during hit-to-lead and lead optimization activities.
- Support rational drug design in collaboration with computational and medicinal chemistry teams.
- Analyze molecular structures, binding interactions and structural data.
- Where applicable, use machine-learning approaches for binding-site prediction or compound prioritization.
Qualification Requirements
Candidates interested in the Meril Structural Biology Intern Recruitment 2026 should preferably have:
- BTech or MTech in Structural Biology, Biophysics, Computational Biology or a related discipline.
- Knowledge of macromolecular structure determination and molecular modeling.
- Understanding of protein structure and protein-ligand interactions.
- Interest in computational drug discovery and rational drug design.
- Knowledge of target validation and lead optimization is desirable.
- Strong presentation and communication skills.
- Ability and willingness to learn new scientific and computational techniques.
Structural Biology & Molecular Modeling Skills
Candidates should have exposure to macromolecular modeling and structure-refinement tools such as:
Phenix, Coot, Chimera and PyMOL
Knowledge of the following areas is also relevant:
- Protein-ligand docking
- Structure validation
- Molecular interaction mapping
- Protein structure analysis
- Structure-based drug design
- Molecular dynamics simulations
- Binding-energy analysis
Molecular Dynamics Tools
Hands-on experience with molecular dynamics software is preferred. Relevant platforms include:
- GROMACS
- AMBER
- NAMD
- CHARMM
Candidates familiar with Schrödinger or AutoDock for structure-based drug design and molecular docking may also be well suited to the position.
Programming Skills
Scripting or programming experience is desirable for automating structural biology workflows and analyzing molecular data.
Relevant technologies include:
- Python
- R
- Bash
Programming skills can be particularly useful for structural-data processing, workflow automation, molecular simulation analysis and computational drug discovery.
Who Should Apply?
This Structural Biology Internship may suit candidates who want to develop careers in:
- Structural Biology
- Computational Biology
- Computational Drug Discovery
- Molecular Modeling
- Bioinformatics
- Biophysics
- Structure-Based Drug Design
- Molecular Dynamics
- Protein Modeling
- Drug Discovery Research
Applicants should carefully compare their academic specialization and technical experience with the requirements stated in the official job posting before applying.
What Meril Offers
According to the job description, selected candidates can expect:
- Exposure to high-impact discovery-stage therapeutic programs.
- Experience working in an interdisciplinary research environment.
- Access to computational and structural biology platforms.
- Opportunities to work on protein structures and ligand-binding problems.
- Exposure to rational and structure-based drug discovery.
- Collaboration with computational and medicinal chemistry teams.
- Potential conversion from internship to a full-time role based on performance.
How to Apply
If you are interested for this job, please share your resume on lisa.kapadia@nuvo.ai
