Thermo Fisher Scientific is a global leader in serving science, committed to enabling customers to make the world healthier, cleaner, and safer. With over 70,000 employees worldwide, we provide innovative solutions in life sciences, healthcare, and applied markets. Our work supports groundbreaking research, drug development, and biomanufacturing, helping scientists and industries achieve their goals faster and more efficiently.
At Thermo Fisher Scientific, we foster a culture of integrity, intensity, innovation, and involvement, ensuring our team members have the support and opportunities to make a meaningful impact.
Job Description
We are seeking a highly motivated Scientist specializing in Upstream Cell Culture to join our Bioprocess Design Center in Hyderabad. This role focuses on developing and optimizing single-use bioreactor systems for biopharmaceutical manufacturing.
Key Responsibilities
Process Development & Optimization
- Design and optimize upstream cell culture processes, including media formulation, feeding strategies, and bioreactor control parameters.
- Conduct small-scale, bench-scale, and pilot-scale experiments to enhance cell growth, productivity, and product quality.
- Evaluate and implement single-use bioreactor technologies to improve process efficiency and flexibility.
Technology Transfer & Scale-Up
- Lead upstream process technology transfer to clinical and commercial manufacturing scales.
- Develop standard operating procedures (SOPs), batch records, and process documentation for scale-up activities.
- Collaborate with manufacturing teams to ensure seamless implementation of upstream processes.
Data Analysis & Documentation
- Analyze experimental data to assess process performance and identify improvement opportunities.
- Prepare technical reports, presentations, and regulatory documentation following Good Documentation Practices (GDP).
- Maintain accurate records in electronic lab notebooks (ELNs).
Cross-Functional Collaboration
- Work closely with downstream processing, analytical development, and quality assurance teams to ensure end-to-end biomanufacturing success.
- Participate in project meetings and contribute to strategic discussions.
- Support troubleshooting of upstream-related challenges in production.
Innovation & Continuous Improvement
- Stay updated on advancements in cell culture technologies and single-use bioprocessing.
- Implement innovative approaches to enhance process scalability and sustainability.
- Foster a culture of continuous improvement within the Bioprocess Design Center.
Qualifications & Experience
Education
- Ph.D., M.S., or B.S. in Biotechnology, Biochemical Engineering, Molecular Biology, or a related field.
Experience
- 3+ years in upstream process development for biologics (mammalian or microbial cell culture).
- Hands-on experience with single-use bioreactor systems (preferred).
- Knowledge of fed-batch, perfusion, and continuous culture processes.
- Familiarity with bioreactor design, process control strategies, and analytical tools.
- Understanding of cGMP guidelines, regulatory standards, and technology transfer.
Preferred Skills
- Experience in cell line development and characterization.
- Knowledge of Process Analytical Technology (PAT) and data-driven optimization tools.
- Strong problem-solving, analytical, and project management skills.
- Excellent communication and presentation skills (English proficiency required).
Why Join Thermo Fisher Scientific?
✅ Competitive salary & annual incentive bonus
✅ Comprehensive healthcare & employee benefits
✅ Career growth & development opportunities
✅ Inclusive & innovative work culture
✅ Global impact in life sciences & healthcare
At Thermo Fisher Scientific, we value diversity and encourage applications from all qualified candidates.
