Are you passionate about advancing biopharmaceutical innovation through oligonucleotide synthesis? Aragen Life Sciences, a leading contract research organization, is hiring skilled professionals for its Oligonucleotides Synthesis – Discovery Solutions department in Hyderabad, Telangana. With a Great Place to Work® certification (Feb 2025–Feb 2026), Aragen offers a dynamic environment for candidates with expertise in nucleic acid chemistry, siRNA, ASOs, and aptamer synthesis. Explore rewarding career opportunities as a Research Associate, Senior Research Associate, Scientific Manager, or Senior Scientific Manager, and contribute to cutting-edge biopharma solutions.
Job Responsibilities
Research Associate / Senior Research Associate
- Synthesize Oligonucleotides: Perform synthesis of siRNA, ASOs, and aptamers using phosphoramidite solid-phase synthesis, solution-phase synthesis, and automated synthesizers like MerMade and AKTA.
- Post-Synthesis Modifications: Execute conjugation, labeling, and annealing processes to meet project specifications.
- Analytical Testing: Conduct quality control using HPLC, LC-MS, UV, and CE to ensure high-purity oligonucleotide batches.
- Equipment Management: Operate and troubleshoot synthesis platforms (MerMade, AKTA, HPLC systems) to maintain workflow efficiency.
- Data Integrity: Maintain accurate records, ensure data quality, and comply with lab protocols.
- Collaboration: Work with cross-functional teams to deliver scalable oligonucleotide batches on time.
- Safety Compliance: Adhere to lab safety standards and regulatory protocols.
Scientific Manager / Senior Scientific Manager
- Lead Synthesis Operations: Oversee production of siRNA, ASOs, and aptamers using advanced synthesis techniques (phosphoramidite, solution-phase, automated systems).
- Project Management: Ensure timely delivery of high-purity oligonucleotides while meeting batch size and project goals.
- Analytical Oversight: Supervise testing (HPLC, LC-MS, UV, CE) and interpret complex data to guide decision-making.
- Troubleshooting: Resolve synthesis and analytical challenges to maintain quality and efficiency.
- Team Leadership: Mentor chemists, manage resources, and optimize project schedules.
- Process Improvement: Drive innovations in synthesis workflows to enhance lab efficiency.
- Documentation & Compliance: Uphold data integrity and ensure adherence to safety and regulatory standards.
Qualifications
Research Associate / Senior Research Associate
- Master’s degree in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field.
- 5–10 years of experience in oligonucleotide synthesis and analysis.
- Strong technical skills in nucleic acid chemistry, purification, and analytical techniques (HPLC, LC-MS, UV, CE).
- Proficiency with automated synthesizers (MerMade, AKTA) and post-synthesis modifications.
- Excellent attention to detail and commitment to data integrity.
Scientific Manager / Senior Scientific Manager
- PhD or Master’s degree in Oligonucleotides, Chemistry, or a related field.
- 7–10 years of experience in oligonucleotide synthesis, with proven leadership in managing teams.
- Expertise in nucleic acid chemistry, purification, and analytical methods (HPLC, LC-MS, UV, CE).
- Strong project management and problem-solving skills.
- Ability to mentor teams and drive process improvements.
Benefits of Working at Aragen
- Great Place to Work® Certified: Join a certified workplace (Feb 2025–Feb 2026) that values innovation and collaboration.
- Career Growth: Opportunities for professional development in a leading biopharma CRO.
- Cutting-Edge Facilities: Work with advanced synthesis platforms and analytical tools.
- Collaborative Environment: Engage with talented teams on impactful biopharma projects.
- Competitive Salary: Earn a competitive salary (₹8,00,000–₹18,00,000 annually, based on experience and role).
- Work-Life Balance: Enjoy a supportive workplace in Hyderabad, a hub for biopharma innovation.
How to Apply
Ready to join Aragen’s Oligonucleotides Synthesis team? Send your resume and cover letter to ravi.bulla@aragen.com with the subject line “Oligonucleotide Synthesis Job Application – [Your Name].” Ensure your application highlights your experience in oligonucleotide synthesis, nucleic acid chemistry, and analytical techniques. Only candidates with relevant experience will be considered. Apply by September 24, 2025, to be part of this exciting opportunity!
FAQs
What qualifications are required for the oligonucleotide synthesis roles at Aragen?
Candidates need a Master’s degree (or PhD for managerial roles) in Chemistry, Biochemistry, or related fields, with 5–10 years of experience in oligonucleotide synthesis and analysis, including expertise in HPLC, LC-MS, and automated synthesizers.
What is the application deadline for these positions?
Applications must be submitted by September 24, 2025, to be considered for these roles.
