If you are looking to build a career in immunology, biologics research, and cell-based assays, this opportunity at Cliantha Research offers hands-on exposure to cutting-edge immunogenicity testing in a state-of-the-art laboratory setup.

Cliantha Research is hiring an Analyst (In-Vitro Immunogenicity) to support their Predictive Immunogenicity Laboratory, focusing on biologics, peptides, and novel therapeutic modalities.

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📌 Job Overview

• Role: Analyst (In-Vitro Immunogenicity)
• Company: Cliantha Research
• Location: Ahmedabad (Sarkhej, Sanand)
• Experience: 1–3 Years
• Employment Type: Full-Time
• Openings: 1

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🔬 Key Responsibilities

1. Assay Development & Execution

• Perform dendritic cell (DC) maturation assays
• Conduct T-cell proliferation and antigen-specific activation assays
• Execute cytokine release assays (ELISA, MSD)
• Support ELISpot / FluoroSpot assays
• Assist in MHC-associated peptide identification (MAPPs) workflows

2. Cell Culture & PBMC Handling

• Handle human PBMCs and donor panels under BSL-2 conditions
• Perform CD14+ monocyte isolation and MoDC differentiation
• Optimize immune cell culture conditions

3. Flow Cytometry Expertise

• Design and optimize multicolor flow cytometry panels
• Perform staining, acquisition, and data analysis
• Analyze markers such as CD80, CD86, CD83, HLA-DR
• Maintain instrument QC and calibration

4. Data & Documentation

• Prepare SOPs, protocols, and technical reports
• Support assay qualification and troubleshooting
• Ensure compliance with scientific and quality standards

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🎓 Qualifications & Eligibility

Educational Requirements

• M.Sc. / M.Tech in:
  • Biotechnology
  • Immunology
  • Life Sciences (related fields)

Experience Required

• 1–3 years of relevant lab experience in immunology or biologics research

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🧪 Required Technical Skills

• Experience in primary immune cell culture (PBMCs, T-cells, monocytes)
• Strong expertise in flow cytometry (panel design & analysis)
• Hands-on experience with:
  • ELISA / MSD
  • ELISpot / FluoroSpot
• Understanding of:
  • Innate & adaptive immune pathways
  • Immunogenicity risk assessment

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⭐ Preferred Skills (Bonus Advantage)

• Knowledge of in-silico epitope prediction tools (NetMHCIIpan, EpiMatrix)
• Experience with:
  • DC biology
  • TLR agonists
  • Biologics immunogenicity studies

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💼 Why Join Cliantha Research?

• Work in a cutting-edge immunogenicity lab
• Exposure to large molecule and biologics research
• Hands-on experience with advanced immunology assays
• Opportunity to contribute to drug development and safety evaluation
• Strong learning and growth environment

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📩 How to Apply

Interested candidates can share their updated CV at:

👉 sdshah@cliantha.com